SynSigSynaptic Signatures
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Enter the HGNC symbol of a gene to search the SynSig database:
- Search Results
- User Guide
- Training Genes
- Predicted Genes
- MO-1200
- Synapse Proteomics Validation
Search the SynSig database to view results here
About SynSig
The synapse is a complex protein-dense structure critical for proper brain functioning. The molecular composition of the synaptic network is incompletely defined, impeding our understanding of healthy and diseased neurological functions. To address this gap, we devised a machine learning system to capture core features of the synapse from their genomic, transcriptomic, and structural patterns – a “synaptic signature” – leading to the identification of novel synaptic proteins.
Manuscript in preparation: Mei et al., "Identifying Synapse Genes Using Global Molecular Signatures."
All code can be found on GitHub.
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